Keep changing the state of play, and wait for either "I don't believe you" or "What just happened?!"
It's about playing your opponent, adapting, make them think you're going for one location and win the other.
Snap by turn 3. You will get a lot of retreats.
Current flex card is Shang-Chi
* Updating with landed combos, and more details.
Location: Bar Sinister
Turn 6 Play Hulk Buster at Bar Sinister to pump it to 19 then play Dr Strange at another location with 2 open slots to pull it for 22 power.