Trump's new DinoNova deck.
Nova gives you a huge buff on everything on the board, so you want to destroy it with Carnage/Deathlok (also Death's Domain or Danger Room).
You also want to have Bucky Barnes at the same location you want to destroy Nova, if possible.
Squirrel Girl is here because is a 3 in 1 card, so even more stuff to buff with Nova.
She is also good to fill locations like Knowhere, Crimson Cosmos, Hellfire Club... but make sure all locations has been revealed before playing her, you could be in a bad situation if some of the locations turn out to be Klyntar, Negative Zone, The Superflow, The Space Throne...
Moon Girl, Sentinel, Cable and Agent 13 helps Devil Dinosaur and The Collector going big(ger).
Iron Man secures locations.
Replacements:
Trump was using Angela instead of The Collector because he was missing him at the time (probably already have it now).
Before unlocking Agent 13 he was using Enchantress, countering opponent's Dino and others ongoing effects (if you intend to use Enchantress, make sure you don't play her at the same location you have a Dino or Iron Man, if you play her before is fine though).
Sorry any typo, english is not my native language 🙃