EDIT: The guide is outdated for now, as I'm currently testing new variations on a daily basis.
Real fun deck I made by mistake when hunting boosters for my commons. It's pretty based on Lockjaw but works pretty well independently as well.
You have 3 main cards dedicated to transforming by Lockjaw: The Hood, Okoye and Ironheart. You can basically transform whatever because the on reveal effects still happen but this is the best value trade.
Okoye gives that little boost for your transformed cards, The Hood's negative power swaps with some card in your deck and you get a nice 1/6 Demon in your hand. Sunspot is there to compensate the lack of plays until you get your hand on Lockjaw.
Spiderman is just a fill I found really useful in this meta, feel free to replace. Shang Chi is just that satisfying IN YO FACE against any high card. I kicked Infinaut in the balls on T6 the other day and oh boy, was it satisfying.
The drill is simple: you play Okoye beside Lockjaw and boom, you have 6, 5, 5 for all your locations with Dr. Doom. Same goes with other high cost cards. 👌
Please let me know if you have an idea for replacements and above all, have fun! ☺️