Change Hulk to Death/Knull if you have them.
Nick Fury and White Queen are flex spots, but I recommend Fury for pool 3 for the off chance you pull Knull, can literally win the game. I would also say Killmonger is a flex, he is there in case you have Nova down and don't pull Carnage or Deathlok from your deck but I rarely find myself using him.
Ideally you have set up at 2 different locations, 1 to setup destruction for Deathlok and then elsewhere for carnage, preferably having Mr Sinister + 1 other card for Carnage. Have 2 locations with a good power lead and then hopefully be able to win the 3rd with Hulk or support your already winning locations. Obviously you won't get this every time but the deck holds out fine with 1 location setup for a destruction. If you get to turn 4 with neither deathlok or carnage in your hand I would recommend retreating.
Try save Nova till as late possible for best use of it.