Thanos

-Bishop and angela gor power to win lanes

-Carnage and Deathlok to clear off bad stones like Time, Space, Mind, Reality.

-Quinjet to reduce cost of stones. Goes into angela or bishop lane unless you need more space or dont need the cost reduction than destroy it.

-Falcon and beast to bounce the stones and useful destroy cards for more space. Also works with angela and bishop for more power. 

-Forge is the flex spot. Any card that adds power and can be bounced is great. Elektra might be good

-Magik extends the game which is great for setting up your lanes or drawing thanos or death.

-Thanos and death are power bombs if you hit them