Negative Calculations

No Inhumans or Psylocke to ramp or get cards out early so I added Quicksilver and Domino for consistency.  With those cards you don't have a chance to get Mr. Negative any more quickly (the math doesn't work out) BUT

1) You get two cards that you can play for 5 total power turns one and two

2) It thins your cards that will be impacted by Mr. Negative - you have a better chance of flipping the cards you want with Mr. Negative since you're always pulling those two cards turns one and two.

3) While by turn three the odds are even for pulling Mr. Negative if you haven't already, you know by turn two if you should retreat if someone pulls an early snap.

Nakia on a flipped Brood gives you 15 power for 2 energy.  Play with Wolfsbane.

Subs
Arnim Zola - Jubilee
Brood - Mister Sinister
Cerebro - Devil Dinosaur